We developed the Human Research Ethics Application (HREA) as a concise application to facilitate timely and efficient ethics review for research involving humans. The HREA assists researchers to consider the ethical principles of the National Statement on Ethical Conduct in Human Research (2007) in relation to their research.

The HREA is free to use. Applications can be made at www.hrea.gov.au.


We have created a range of resources for using HREA, including frequently asked questions, user guides, ‘how to’ videos and workshop slides.

Acceptance of HREA by institutions in the NMA Scheme

A National Mutual Acceptance (NMA) Scheme for ethics review operates in some states and territories. The NMA Scheme allows for the acceptance of a single ethics review by multiple public health organisations for most human research.

Research proposals should be submitted via ERMResearch GEM and REGIS to Human Research Ethics Committees (HRECs) associated with public health institutions in the following jurisdictions: New South Wales, Queensland, South Australia, Australian Capital Territory, Victoria, as well as Mater Research (Brisbane, Qld). Researchers who start their ethics application at www.hrea.gov.au can generate an XML file that can be imported into Research GEM.

If you are submitting a research proposal to an HREC that is located in the Northern Territory, Tasmania or Western Australia, please contact that HREC to obtain their local submission requirements (if they are not listed in the HREA Directory).

For further information on the NMA Scheme, contact the relevant public hospital HREC or the state/territory Department of Health office: