As part of the Australian Government’s response to potential per-and poly fluoroalkylated substances (PFAS) contamination on or near Commonwealth sites, a national research program into the human health effect of PFAS has been established.
PFAS has been found at a number of sites around Australia and in food and drinking water from these areas. There has been significant community concern about the potential health impacts from exposure to PFAS.
A TCR is a one-time solicitation for grant applications to address a specific health issue. A TCR will stimulate or greatly advance research in a particular area of health and medical science that will benefit the health of Australians. NHMRC anticipates that a TCR on this subject will commence in late 2018.
NHMRC has established the PFAS TCR Reference Group to assist with the background work required to develop the TCR. This group will inform the development of the PFAS TCR research questions/s, objectives and selection criteria, based on consideration of current, high quality scientific data, government and regulatory authority reports (national and International) as well as a report provided by an Expert Health Panel established by the Department of Health. The Reference Group will identify what research will be within the scope of the TCR and provide contextual information on the background, aims and desired outcomes of the TCR.
The PFAS TCR Reference Group includes a range of scientific experts.
|Name/Position||Area of Expertise||Declaration of Interest|
A/Professor Barry Noller(Chair)
|Associate Professor Barry Noller has expertise in environmental toxicology; pollution control; toxicology, chemicals in the environment, water pollution, soil pollution, health risk assessment; environmental chemistry and aquatic pollution.||An expert witness for the Commonwealth of Australia, Department of Defence regarding Williamtown and Oakey chemical contamination attributed to the use of aqueous film forming foam (a fire suppressant agent) and its effects on the environment, which contains PFAS.|
|Professor Lisa Bero||Professor Lisa Bero, is a researcher in evidence-based health care at the University of Sydney. She is internationally renowned for her studies on the integrity of clinical and basic research evidence that is used to influence health policy. Professor Bero directs the multidisciplinary Evidence, Policy and Influence Collaborative at the Charles Perkins Centre and is a current member of NHMRC’s Synthesis and Translation of Research Evidence Advisory Group.||
Published extensively on methods for systematic reviews and risk of bias assessment, impact of conflicts of interest and funding sources on the design, conduct and publication of research.
Professor Jane Heyworth
|Professor Jane Heyworth has expertise in environment epidemiology; environmental health research, policy and practice; population health; environmental risk factors; water quality; air pollution and chemical exposure cancer epidemiology. She is currently Deputy Head of the School of Population and Global Health, Faculty of Health and Medical Sciences at the University of Western Australia.||
Has published on maternal exposure to perfluoralkyl acids and birth outcomes in 2016. Maternal exposure to Perfluoralkyl acids measured in whole blood and birth outcomes in offspring.Numerous publications on persistent organic compounds in the last 5 years
|Professor Brian Priestly||Professor Brian Priestly has expertise in toxicology, environmental health risk assessment, environmental pollutants and risk perception. He was the inaugural Director of the Australian Centre for Human Health Risk Assessment (ACHHRA). ACHHRA is now affiliated with the Monash Centre for Occupational & Environmental Health and its mission is to provide a national focus for environmental health risk assessment, primarily in the area of food and environmental pollutants.||
Contracted reviews of health effects of PFOS and related substances for the Victorian Dept of Health & Human Services; 2015, 2016, 2017.
Participation in enHealth workshops considering health-based guidance values (HBGV) for PFAS; 2015-2016.
Peer review of draft FSANZ reports used to establish PFAS TDI values; 2016.
Appearance before the Victorian Parliamentary Inquiry into Fiskville; 2015.
Member of CRC-CARE Program Advisory Committee developing PFAS HHRA and clean-up guidance; 2015-2018.
|Dr Christos Symeonides||Dr Christos Symeonides is a paediatrician from the Murdoch Children’s Institute. Has expertise in chemical exposure in utero and infancy and environmental toxicology.||Is employed as a General & Developmental Paediatrician at both the Royal Children’s Hospital, Melbourne, and in private practice in Melbourne, and as a Research Officer at the Murdoch Children’s Research Institute.|
|Dr Justin Hamilton||Community Representative - Fullerton Cove NSW||
|Dr Peter Spafford||Community Representative - Katherine NT||
|Ms Kim Smith||Community Representative - Salt Ash NSW||
|Ms Dianne Priddle||Community Representative - Oakey QLD||
NHMRC has well defined procedures for the establishment of Reference Groups which are based on obtaining the best experts available while ensuring conflicts of interest (real and perceived) are managed appropriately.
NHMRC does not allow people to apply to a TCR if they have assisted with the development of the research question or associated policies of that TCR. This requirement has been taken into consideration when identifying potential Reference Group members.
The Reference Group will not review the research applications that will be submitted to the TCR. That role will be performed by a separate peer review committee of scientific experts. However, members of the Advisory Committee may be invited to participate in the peer review assessment process for the TCR, if required at the time.
(This section will be updated regularly following Reference Group meetings and as otherwise appropriate).
- The first meeting of the Reference Group Committee occurred on 6 June 2018. Members considered the EHP Report and Identified priority research themes.
- The second meeting of the Reference Group Committee occurred on 6 August 2018. Members discussed previously identifies research and themes in depth.
- The third meeting of the Reference Group Committee is scheduled for 8 October 2018. The Reference Group has sought community representation from Williamtown, Oakey and Katherine councils to ensure the research agenda considers the concerns of PFAS affected communities. The community representatives will advise the Reference Group on those issues relating to human health that need further investigation. Their input will inform further refinement of the research themes.
- The fourth meeting of the Reference Group Committee occured on 19 November to finalise the identified research areas and themes.
Terms of Reference
Established under section 39 of the National Health and Medical Research Council (NHMRC) Act 1992, the Reference Group regarding Per- and Poly-fluoroalkylated substances will advise on the objectives, desired outcomes and selection criteria of the grant opportunity.
This will be achieved by:
- Considering the advice provided by the Department of Health’s Expert Health Panel.
- Identifying any gaps in the research evidence that would increase an understanding of how PFAS exposure may affect human health.
Peer Review Information
Information on the Targeted Call for Research peer review process can be found in the 2018 Targeted Call for Research scheme-specific peer review guidelines.
2018 Targeted Call for Research scheme-specific peer review guidelines - see Downloads.
Outcomes of funding rounds
Outcomes for Targeted Calls for Research are available here.
Queries about the work of the Advisory Committee should be directed to firstname.lastname@example.org