NHMRC Guidelines for Monoclonal Antibody Production

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These guidelines have been developed by NHMRC on advice from its Animal Welfare Committee in response to the growing need for further emphasis on the principles of Replacement and Refinement as they apply to the use of animals for the production of monoclonal antibodies. These guidelines also assist institutional Animal Ethics Committees in the evaluation of applications involving monoclonal antibody production.

This document should be read in conjunction with the Australian Code for the Care and Use of Animals for Scientific Purposes 8th edition (2013).

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