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NHMRC Guidelines for Monoclonal Antibody Production

The basic message contained within the Guidelines, which were an initiative of the NHMRC Animal Welfare Committee (AWC), is that the use of the ascites fluid method for the production of monoclonal antibodies (MAbs) is no longer acceptable.

Summary download document information:

Published year: 2008
Available in print: No
Status: Current

Reference No: EA19
Further information: nhmrc.publications@nhmrc.gov.au

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» Download: NHMRC Guidelines for Monoclonal Antibody Production (PDF, 3,155kb) pdf file

Synopsis of publication:

This document was developed in response to recognition of the growing need for further emphasis on the principles of Replacement and Refinement as they apply to the use of animals for the production of monoclonal antibodies.

The NHMRC Animal Welfare Committee has developed the following guidelines to assist institutional Animal Ethics Committees in the evaluation of applications involving monoclonal antibody production.

This document should be read in conjunction with The Australian Code of Practice for the Care and Use of Animals for Scientific Purposes which is available from : http://www.nhmrc.gov.au/publications/synopses/ea16syn.htm

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