The Letter of Intent is a document including your scientific proposal, details of the research environment, people involved and references. Your Letter of Intent should indicate how your proposal fits the call specification for this scheme.
The Letter of Intent should not exceed five sides of A4 plus one additional page of references (six pages in total). Please use:
- Arial font with a minimum size of 11pt (excluding text on diagrams or mathematical symbols)
- A minimum of single line spacing
- Standard character spacing
- Margins of no less than 2cm.
- Please number all pages of the Letter of Intent.
Your Letter of Intent may be removed from consideration if these formatting requirements are not observed.
If you plan to include unpublished data it must be included in the Letter of Intent. Manuscripts in press or submitted to journals should not be included. Please refer to the assessment criteria for this scheme when completing your Letter of Intent.
Applications for grants will be assessed against the following criteria:
- Relevance and Quality of Project (25%)
- Quality of Team (25%)
- Project Implementation Plans (25%)
- Potential Impact (25%)
Criterion One: Relevance and Quality of Project
- Proposal fits well within the objectives and scientific remit set out in the call.
- Strong scientific rationale for pursuing the questions or gaps in knowledge that are being addressed. Success is likely to lead to significant new understanding that is relevant for scientists and knowledge users. Applicants are aware of complementary research underway elsewhere.
- Proposed methods are appropriate and feasible to answer the study question(s) and are considered best in the international field of implementation science research (e.g. mixed methods designs, in-depth comparative case studies, pragmatic cluster RCTs, and natural experiments).
- Proposal is innovative (applicants may want to refer to the document on integrated innovation - http://www.grandchallenges.ca/wordpress/wp-content/uploads/integratedinnovation_EN.pdf)
- Intervention has been adequately described.
Criterion Two: Quality of Team
- Multidisciplinary team members have established a high quality track record in related fields of proposed research and pertinent to implementation science and they have the right balance of expertise given goal(s) of research project.
- Each country participating in the project must have a named principal investigator.
- Early career investigators are part of the team and strong training plan for research capacity-building is included.
- Demonstrated engagement of decision-makers.
Criterion Three: Project Implementation Plans
- Major scientific, technical or organisational challenges been identified, and realistic plans to tackle these are outlined.
- Proposed intervention strategies are relevant to the socio-political, cultural, legislative and economic contexts of the study settings.
- Inequities and equity gaps including gender have been taken into account in the design of an implementation strategy.
- Objective measures of evaluation have been included. Programmes that are able to track long-term clinical, policy and/or health system outcomes are strongly encouraged.
Criterion Four: Potential Impact
- Project demonstrates alignment with international and/or national commitments to halt the rise in prevalence of type 2 diabetes.
- Project appropriately leverages existing programmes and platforms (e.g. research, data, delivery platforms)
- The potential for scaling up intervention strategies has been considered. For example, applicants could address affordability for users and the financial implications for implementing organisations and funders or might assess scalability to various socio-political contexts.
- Projects are designed to inform practice, programmes and/or policy development and/or refinements.
- Describe how health economic dimensions will be assessed such as cost-effectiveness of proposed intervention and its scalability.
All applications must describe:
- System barriers (health care and other) to treatment and prevention of type 2 diabetes and how these can be addressed
- System facilitators and how these will be leveraged
- How decision-makers and other knowledge users will be engaged in the project
- An implementation research component - implementation should involve some strategies with demonstrated efficacy and/or effectiveness and may also include the development of new strategies
- An assessment of equity and gender gaps and the needs of vulnerable populations** in treatment and prevention of type 2 diabetes
- The multidisciplinary composition of research teams
- An appropriate plan for knowledge translation and exchange as a component of the project
- Training plan for research capacity building
Please use the following headings when preparing your outline Letter of Intent
- Project summary information
- Full title of the project (no more than 150 characters)
- Administering Institution
- In which country (ies) will the project take place
- Duration in months (maximum 60mths)
- Total amount requested
- Principal research question(s) to be addressed
- Project description
Please describe the methodology to be used. Please ensure that you cover the following points:
- Where will the research take place?
- What implementation science research questions will be addressed?
- How will scale up be addressed?
- Who will the research participants be and why?
- What decision-making partners will be involved?
- If the study is with Aboriginal populations, demonstrate how the project will have relevant community engagement by individuals, communities and/or organisations and the potential health benefit of the project for Aboriginal peoples. What are your research plans to address those questions?
- Give details of the experimental approaches, study design and techniques that will be used.
- Enough detail must be given to show why the research is likely to be competitive in its field.
- Please ensure that you have clearly described the intervention and, if relevant, the control or counterfactual.
- If the research involved data collection or acquisition you must demonstrate that you have carried out a datasets review, and state why currently available datasets are inadequate for the proposed research.
- What is the proposed timeline?
- How will you evaluate the outcome of the study?
- Rationale for the study
Please indicate how your project fits the objectives and scope of the call specification.
Why is the study needed now and in the proposed location?
Please consider issues such as burden of disease and priority for the relevant local, regional and national health services.
What gaps in existing knowledge will be addressed by the study and why is addressing those gaps using an implementation science approach important?
What evidence is that the answer to your research question is needed and wanted by relevant users, for instance, policy-makers
- Research project team and Engagement Strategies
Please indicate the level and nature of involvement of multidisciplinary research teams, clinical and non-clinical health workers, civil society, industry, policy and decision makers and patient and community groups.
Please describe how the team of investigators incorporate the range of discipline and experience necessary to carry out the study
- How will the results of this study be used?
What changes might be implemented as a result of this study?
Who will make those changes happen and how?
Might the results be generalizable beyond the immediate research setting?
What are the planned knowledge translation strategies?
(NB Detailed budgets and administrative information to be collected separately by each agency.)